BP504T. PHARMACOGNOSY AND PHYTOCHEMISTRY II Books
“Pharmacognosy and Phytochemistry II: Natural products in medicine, including plant and animal-derived drugs and bioactive compounds.”
Course Content
Unit Title
Content
UNIT-I
- Metabolic pathways in higher plants and their determination
- a) Brief study of basic metabolic pathways and formation of different secondary metabolites through these pathways- Shikimic acid pathway, Acetate pathways and Amino acid pathway.
- b) Study of utilization of radioactive isotopes in the investigation of Biogenetic studies.
UNIT-II
- General introduction, composition, chemistry & chemical classes, biosources, therapeutic
uses and commercial applications of following
secondary metabolites: - Alkaloids: Vinca, Rauwolfia, Belladonna, Opium,
- Phenylpropanoids and Flavonoids: Lignans, Tea, Ruta
Steroids, Cardiac Glycosides & Triterpenoids: Liquorice, Dioscorea, Digitalis - Volatile oils: Mentha, Clove, Cinnamon, Fennel, Coriander,
- Tannins: Catechu, Pterocarpus
- Resins: Benzoin, Guggul, Ginger, Asafoetida, Myrrh, Colophony
- Glycosides: Senna, Aloes, Bitter Almond
- Iridoids, Other terpenoids & Naphthaquinones: Gentian, Artemisia, taxus, carotenoids
UNIT-III
- Isolation, Identification and Analysis of Phytoconstituents
a) Terpenoids: Menthol, Citral, Artemisin
b) Glycosides: Glycyrhetinic acid & Rutin
c) Alkaloids: Atropine,Quinine,Reserpine,Caffeine
d) Resins: Podophyllotoxin, Curcumin
UNIT-IV
- Industrial production, estimation and utilization of the following phytoconstituents
- Forskolin, Sennoside, Artemisinin, Diosgenin, Digoxin, Atropine, Podophyllotoxin, Caffeine, Taxol, Vincristine and Vinblastine
UNIT-V
- Basics of Phytochemistry
- Modern methods of extraction, application of latest techniques like Spectroscopy, chromatography and electrophoresis in the isolation, purification and identification of crude
drugs.
Learning Objectives
- To know the modern extraction techniques, characterization and identification of the herbal drugs and phytoconstituents
- To understand the preparation and development of herbal formulation
- To understand the herbal drug interactions
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