BP503T. PHARMACOLOGY-II Books
“Pharmacology II: Advanced topics in pharmacology, including systemic pharmacology, complex drug classes, drug interactions, and toxicity. Exploring the science of drug action and its clinical applications.”
Course Content
Unit Title
Content
UNIT-I
- Pharmacology of drugs acting on cardio vascular system
a. Introduction to hemodynamic and electrophysiology of heart.
b. Drugs used in congestive heart failure
c. Anti-hypertensive drugs.
d. Anti-anginal drugs.
e. Anti-arrhythmic drugs.
f. Anti-hyperlipidemic drugs.
UNIT-II
- 1. Pharmacology of drugs acting on cardio vascular system
a. Drug used in the therapy of shock.
b. Hematinics, coagulants and anticoagulants.
c. Fibrinolytics and anti-platelet drugs
d. Plasma volume expanders - 2. Pharmacology of drugs acting on urinary system
a. Diuretics
b. Anti-diuretics
UNIT-III
- 3. Autocoids and related drugs
a. Introduction to autacoids and classification
b. Histamine, 5-HT and their antagonists.
c. Prostaglandins, Thromboxanes and Leukotrienes.
d. Angiotensin, Bradykinin and Substance P. e. Non-steroidal anti-inflammatory agents
f. Anti-gout drugs
g. Antirheumatic drugs
UNIT-IV
- 5. Pharmacology of drugs acting on endocrine system
a. Basic concepts in endocrine pharmacology. b. Anterior Pituitary hormones- analogues and their inhibitors.
c. Thyroid hormones- analogues and their inhibitors.
d. Hormones regulating plasma calcium level- Parathormone, Calcitonin and
Vitamin-D.
d. Insulin, Oral Hypoglycemic agents and glucagon.
e. ACTH and corticosteroids.
UNIT-V
- 5. Pharmacology of drugs acting on endocrine system
a. Androgens and Anabolic steroids.
b. Estrogens, progesterone and oral contraceptives.
c. Drugs acting on the uterus. - 6. Bioassay
a. Principles and applications of bioassay. b.Types of bioassay
c. Bioassay of insulin, oxytocin, vasopressin, ACTH,d-tubocurarine,digitalis, histamine
and 5-HT
Learning Objectives
- Understand the mechanism of drug action and its relevance in the treatment of different diseases
- Demonstrate isolation of different organs/tissues from the laboratory animals by simulated experiments
- Appreciate correlation of pharmacology with related medical sciences
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