Dopamine is a neurotransmitter and medication that plays a crucial role in various physiological processes. Here is a detailed description:
Chemical Name: 4-(2-Aminoethyl)benzene-1,2-diol
Molecular Formula: C8H11NO2
Mechanism of Action:
- Neurotransmitter: Dopamine regulates mood, motivation, movement, and reward processing by stimulating dopamine receptors in the brain.
- Medication: Dopamine increases cardiac output, blood pressure, and renal perfusion by stimulating dopamine receptors in the heart and blood vessels.
Indications:
- Neurotransmitter:
- Mood regulation
- Motivation
- Movement control
- Reward processing
- Medication:
- Shock
- Cardiac arrest
- Heart failure
- Low blood pressure (hypotension)
Pharmacokinetics:
- Absorption: Rapidly absorbed after injection
- Distribution: Widely distributed throughout the body
- Metabolism: Metabolized by monoamine oxidase (MAO) and catechol-O-methyltransferase (COMT)
- Excretion: Excreted in the urine
Side Effects:
- Headache
- Nausea and vomiting
- Anxiety
- Agitation
- Insomnia
- Increased heart rate and blood pressure
Contraindications:
- Hypersensitivity to Dopamine
- Pheochromocytoma (adrenal gland tumor)
- Uncorrected tachyarrhythmias (abnormal heart rhythms)
Dosage: avoid self medication
- Injection: 2-5 mcg/kg/min, titrated to effect
Forms:
- Injection
- Infusion
Please note that this information is not a substitute for medical advice. If you have any questions or concerns about Dopamine or any other medication, please consult a healthcare professional.