PROPRANOLOL

Propranolol is a non-selective beta-blocker used to treat a variety of conditions, including hypertension, angina, certain types of tremors, and anxiety. It works by blocking beta-adrenergic receptors, which helps to lower blood pressure, reduce heart rate, and decrease the workload on the heart. Propranolol is also used in the management of migraine prophylaxis and in some cases of arrhythmias. It is typically administered orally in tablet form but can also be given intravenously. Common side effects include fatigue, dizziness, and gastrointestinal disturbances. It should be used cautiously in patients with respiratory conditions or certain heart conditions.

Propranolol is a medication that belongs to the class of beta-blockers. Here is a detailed description:

Chemical Name: 1-(Isopropylamino)-3-(1-naphthyloxy)propan-2-ol

Molecular Formula: C16H21NO2

Mechanism of Action:

  • Propranolol works by blocking beta-adrenergic receptors, reducing heart rate, blood pressure, and myocardial contractility.

Indications:

  • Hypertension (high blood pressure)
  • Angina pectoris (chest pain)
  • Cardiac arrhythmias (abnormal heart rhythms)
  • Migraine prophylaxis
  • Essential tremor
  • Performance anxiety

Pharmacokinetics:

  • Absorption: Well absorbed after oral administration
  • Distribution: Widely distributed throughout the body
  • Metabolism: Metabolized in the liver
  • Excretion: Excreted in the urine

Side Effects:

  • Fatigue
  • Dizziness
  • Bradycardia (slow heart rate)
  • Hypotension (low blood pressure)
  • Bronchospasm (asthma exacerbation)

Contraindications:

  • Hypersensitivity to Propranolol
  • Severe bradycardia
  • Heart block
  • Cardiogenic shock
  • Severe asthma
  • Pregnancy (caution)

Dosage: avoid self medication

  • Oral: 20-640 mg, every 6-12 hours

Forms:

  • Tablets
  • Capsules
  • Solution

Please note that this information is not a substitute for medical advice. If you have any questions or concerns about Propranolol or any other medication, please consult a healthcare professional.