METIPRANOLOL

Metipranolol is a non-selective beta-blocker primarily used in ophthalmology to treat elevated intraocular pressure in conditions like open-angle glaucoma and ocular hypertension. It works by reducing the production of aqueous humor in the eye, thereby lowering intraocular pressure. Metipranolol is typically administered as eye drops. Common side effects can include ocular irritation, dry eyes, and potential systemic effects like fatigue or dizziness. It should be used under medical supervision, especially in individuals with cardiovascular or respiratory conditions.

Metipranolol is a non-selective beta-adrenergic receptor blocker, primarily used to treat:

Glaucoma: Reduces intraocular pressure by decreasing aqueous humor production.
Hypertension: Lowers blood pressure by reducing cardiac output and peripheral resistance.

Chemical Name: 1-[4-(2-hydroxyethyl)phenoxy]-3-(isopropylamino)propan-2-ol

Molecular Formula: C12H17NO3

Metipranolol has a:

Half-life: 7-10 hours
Bioavailability: 75-80%
Metabolism: Hepatic, primarily through CYP2D6

Common side effects:

Fatigue
Dizziness
Headache
Nausea
Bradycardia (slow heart rate)

Contraindications:

Severe bradycardia
Heart block
Cardiogenic shock
Severe chronic obstructive pulmonary disease (COPD)

Please note that this information is for educational purposes only and should not be used as medical advice. If you have any questions or concerns about Metipranolol or any other medication, please consult a healthcare professional.