M. Pharmacy Quiz-37

Arrange the following drug discovery steps in correct order: 1.Target validation 2.Lead optimization 3.Lead identification 4.Target identification

4 → 1 → 3 → 2

1 → 4 → 2 → 3`

4 → 3 → 1 → 2

3 → 4 → 1 → 2

Economics of drug discovery mainly deals with:

Mechanism of drug action

Cost, time, and resources required in discovery and development

Drug-receptor interactions

Screening assays

Which stage of drug discovery focuses on improving the potency, selectivity, and safety of a lead compound?

Target validation

Lead identification

Lead optimization

Economics of drug discovery

Lead identification in drug discovery mainly involves:

Screening compounds to find potential candidates

Optimizing the pharmacokinetic properties of a drug

Conducting human clinical trials

Confirming disease relevance of the target

The process of confirming that a biological target is directly involved in a disease and can be modulated by a drug is called:

Lead optimization

Target validation

Pharmacogenomics

Preclinical testing

M. Pharmacy Quiz-37

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