Disease Related

BITOLTEROL

Bitolterol is a bronchodilator medication used to treat asthma and chronic obstructive pulmonary disease (COPD). It helps relax the muscles in the airways, making it easier to breathe. Typically administered via an inhaler, Bitolterol works by stimulating beta-adrenergic receptors in the lungs, leading to airway dilation and reduced respiratory symptoms.

Chemical Name: 4-[2-[[(1,1-Dimethylethyl)amino]methyl]-4-hydroxyphenyl]-2-(tert-butyl)pyridine-3-carboxylic acid

Molecular Formula: C24H31NO4

Mechanism of Action:

  • Bitolterol works by stimulating beta-2 adrenergic receptors, leading to:
    • Relaxation of bronchial muscles
    • Increased heart rate
    • Increased blood sugar levels

Indications:

  • Asthma
  • Chronic obstructive pulmonary disease (COPD)
  • Exercise-induced bronchospasm

Pharmacokinetics:

  • Absorption: Rapidly absorbed after inhalation
  • Distribution: Widely distributed throughout the body
  • Metabolism: Metabolized in the liver
  • Excretion: Excreted in the urine

Side Effects:

  • Tremors
  • Anxiety
  • Headache
  • Palpitations
  • Nausea and vomiting

Contraindications:

  • Hypersensitivity to Bitolterol
  • Uncontrolled hypertension
  • Severe tachyarrhythmias
  • Heart disease

Dosage: avoid self medication

  • Inhalation: 2-4 puffs, every 6-8 hours

Forms:

  • Inhaler

Note: Bitolterol is no longer marketed in many countries due to concerns about its safety and efficacy. Other medications, such as albuterol, are preferred for treating asthma and COPD.

Please note that this information is not a substitute for medical advice. If you have any questions or concerns about Bitolterol or any other medication, please consult a healthcare professional.