CARVEDILOL

Carvedilol is a non-selective beta-blocker with alpha-1 blocking activity, used to treat conditions such as hypertension and heart failure. It works by reducing heart rate and blood pressure while also dilating blood vessels, which helps lower overall blood pressure and reduce the heart’s workload. Carvedilol is typically administered orally in tablet form. Common side effects include dizziness, fatigue, and fluid retention. It should be used with caution in patients with respiratory conditions, diabetes, or certain heart issues.

Carvedilol is a medication that belongs to the class of beta-blockers and alpha-blockers. Here is a detailed description:

Chemical Name: 1-(9H-carbazol-4-yloxy)-3-[[2-(2-methoxyphenoxy)ethyl]amino]-2-propanol

Molecular Formula: C24H26N2O4

Mechanism of Action:

Carvedilol works by blocking beta-1 and beta-2 adrenergic receptors, reducing heart rate and blood pressure, and also by blocking alpha-1 adrenergic receptors, causing vasodilation.

Indications:

Hypertension (high blood pressure)
Heart failure
Left ventricular dysfunction after myocardial infarction (heart attack)

Pharmacokinetics:

Absorption: Well absorbed after oral administration
Distribution: Widely distributed throughout the body
Metabolism: Metabolized in the liver
Excretion: Excreted in the urine and feces

Side Effects:

Fatigue
Dizziness
Headache
Nausea and vomiting
Bradycardia (slow heart rate)
Hypotension (low blood pressure)

Contraindications:

Hypersensitivity to Carvedilol
Severe bradycardia
Heart block
Cardiogenic shock
Severe asthma
Pregnancy (caution)

Dosage: avoid self medication

Oral: 3.125-50 mg, twice daily

Forms:

Tablets
Capsules

Please note that this information is not a substitute for medical advice. If you have any questions or concerns about Carvedilol or any other medication, please consult a healthcare professional.