DOBUTAMINE

Dobutamine is a medication used to treat heart failure and cardiogenic shock. It works by stimulating beta-1 adrenergic receptors in the heart, increasing cardiac output and improving blood flow.

Dobutamine is a medication used to treat heart failure and cardiogenic shock. Here is a detailed description:

Chemical Name: 4-[2-[[3-(4-hydroxyphenyl)-1-methylpropyl]amino]ethyl]pyrocatechol

Molecular Formula: C18H23NO3

Mechanism of Action:

Dobutamine works by stimulating beta-1 and beta-2 adrenergic receptors, leading to:
- Increased heart rate and contractility
- Increased cardiac output
- Decreased peripheral vascular resistance

Indications:

Heart failure
Cardiogenic shock
Cardiac surgery
Heart transplantation

Pharmacokinetics:

Absorption: Rapidly absorbed after injection
Distribution: Widely distributed throughout the body
Metabolism: Metabolized in the liver
Excretion: Excreted in the urine

Side Effects:

Rapid heartbeat
Palpitations
Hypertension
Anxiety
Headache
Nausea and vomiting

Contraindications:

Hypersensitivity to Dobutamine
Uncontrolled hypertension
Severe tachyarrhythmias
Heart block

Dosage: avoid self medication

Injection: 2.5-10 mcg/kg/min, titrated to effect

Forms:

Injection

Please note that this information is not a substitute for medical advice. If you have any questions or concerns about Dobutamine or any other medication, please consult a healthcare professional.