ESMOLOL

Esmolol is a selective beta-1 adrenergic blocker used primarily in acute settings to manage rapid heart rates, such as during surgery or in emergency situations. It works by decreasing heart rate and blood pressure. Esmolol is administered intravenously due to its short half-life, allowing for precise control of dosing and rapid adjustments. Common side effects include hypotension, bradycardia, and dizziness. It should be used with caution in patients with certain cardiac conditions or respiratory issues.

Esmolol is a medication that belongs to the class of beta-blockers. Here is a detailed description:

Chemical Name: methyl 3-[4-[2-hydroxy-3-(isopropylamino)propoxy]phenyl]propanoate

Molecular Formula: C16H25NO4

Mechanism of Action:

Esmolol works by blocking beta-1 adrenergic receptors, reducing heart rate, and decreasing blood pressure.

Indications:

Supraventricular tachycardia (abnormal heart rhythm)
Intraoperative and postoperative tachycardia and hypertension
Hypertension (high blood pressure)

Pharmacokinetics:

Absorption: Rapidly absorbed after intravenous administration
Distribution: Widely distributed throughout the body
Metabolism: Metabolized by esterases in the blood
Excretion: Excreted in the urine

Side Effects:

Hypotension (low blood pressure)
Bradycardia (slow heart rate)
Nausea and vomiting
Headache
Fatigue

Contraindications:

Hypersensitivity to Esmolol
Severe bradycardia
Heart block
Cardiogenic shock
Severe asthma
Pregnancy (caution)

Dosage: avoid self medication

Intravenous: 50-200 mcg/kg/min

Forms:

Injection

Please note that this information is not a substitute for medical advice. If you have any questions or concerns about Esmolol or any other medication, please consult a healthcare professional.