Disease Related

HYDROXYAMPHETAMINE

Hydroxyamphetamine is a medication primarily used in ophthalmology. It is commonly employed in eye drops to assess pupil dilation and the functionality of the autonomic nervous system. By stimulating the release of norepinephrine from nerve endings, Hydroxyamphetamine causes pupil dilation and can help diagnose various eye conditions. It is often used in conjunction with other agents to perform comprehensive eye examinations.

The chemical name for Hydroxyamphetamine is: 4-(2-Amino-1-hydroxyethyl)phenol

Molecular Formula: C8H11NO2

Hydroxyamphetamine is a metabolite of amphetamine and a precursor to norepinephrine. It’s a sympathomimetic agent, which means it mimics the effects of the sympathetic nervous system, including increased heart rate, blood pressure, and energy.

Indications:

  • Hydroxyamphetamine is not typically used as a medication, but its parent compound, amphetamine, is used to treat:
    • Attention Deficit Hyperactivity Disorder (ADHD)
    • Narcolepsy
    • Obesity (short-term)

Mechanism of Action:

  • Hydroxyamphetamine increases the release of norepinephrine and other neurotransmitters, leading to increased stimulation and alertness.

Pharmacokinetics:

  • Absorption: Rapidly absorbed after oral administration
  • Distribution: Widely distributed throughout the body
  • Metabolism: Metabolized in the liver
  • Excretion: Excreted in the urine

Side Effects:

  • Increased heart rate and blood pressure
  • Increased energy and alertness
  • Insomnia
  • Anxiety
  • Nausea and vomiting

Contraindications:

  • Hypersensitivity to amphetamines
  • Severe anxiety or agitation
  • Glaucoma
  • History of substance abuse

Please note that this information is for educational purposes only and should not be used as medical advice. If you have any questions or concerns about Hydroxyamphetamine or any other medication, please consult a healthcare professional.