M. Pharmacy Quiz-10

What is the primary mechanism of action of Sulfonylureas?

Activating AMP-activated protein kinase (AMPK)

Inhibiting glucose absorption in the gut

Stimulating insulin release from pancreatic beta cells by blocking potassium channels

Increasing glucose excretion in the urine

Which of the following oral hypoglycemic agents works by inhibiting DPP-4 enzyme?

Metformin

Sulfonylureas

Sitagliptin

Pioglitazone

What is the mechanism of action of Pioglitazone?

Activating PPAR-Y, increasing insulin sensitivity

Inhibiting glucose absorption in the gut

Stimulating insulin release from pancreatic beta cells

Increasing glucose excretion in the urine

Which of the following oral hypoglycemic agents works by inhibiting SGLT2 in the kidneys?

Metformin

Sitagliptin

Canagliflozin

Sulfonylureas

What is the effect of Metformin on glucose production in the liver?

Increases glucose production

Decreases glucose production by inhibiting gluconeogenesis

Has no effect on glucose production

Increases glucose storage

M. Pharmacy Quiz-10

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