M. Pharmacy Quiz-24

Which of the following is a Neurokinin-1 (NK1) receptor antagonist used in chemotherapy-induced nausea and vomiting?

Aprepitant

Granisetron

Promethazine

Domperidone

Dronabinol, used in refractory chemotherapy-induced nausea and vomiting, is a:

Dopamine antagonist

Cannabinoid receptor agonist

Histamine H1 antagonist

Muscarinic antagonist

Which of the following antiemetic drugs is most effective in motion sickness?

Ondansetron

Scopolamine

Metoclopramide

Domperidone

Metoclopramide acts as an antiemetic primarily by:

Blocking 5-HT3 receptors in the gut

Stimulating dopamine D2 receptors

Blocking dopamine D2 receptors in the chemoreceptor trigger zone

Blocking histamine H1 receptors in the vestibular system

Which of the following receptors is mainly targeted by Ondansetron for its antiemetic effect?

Dopamine D2 receptors

Muscarinic receptors

Histamine H1 receptors

5-HT3 receptors

M. Pharmacy Quiz-24

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