M. Pharmacy Quiz-44

Which of the following best describes a key difference between traditional and rational drug design?

Traditional drug design uses predictive modeling

Rational drug design depends on random screening

Traditional drug design focuses on natural product screening

Rational drug design relies on crude extract testing

What is the first step in rational drug design?

Lead identification

Clinical trials

Disease target selection

In vivo testing

Which of the following is not a method used in structure-based drug design?

X-ray crystallography

Molecular docking

NMR spectroscopy

Ligand-based design

X-ray crystallography provides What is a major advantage of rational drug design over traditional drug design?

Increased randomness in discovery

Static 3D Reduced time and attrition rate

Use of only natural products

Absence of computational tools

Which of the following techniques helps visualize the 3D structure of target proteins?

Cryo-EM

PCR

ELISA

HPLC

M. Pharmacy Quiz-44

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