Phenylephrine is a medication used as a decongestant and vasopressor. Here is a detailed description:
Chemical Name: (R)-3-[(1-Hydroxy-2-methylaminoethyl)phenol]
Molecular Formula: C9H13NO2
Mechanism of Action:
- Decongestant: Phenylephrine reduces nasal congestion by constricting blood vessels in the nose, sinuses, and eyes.
- Vasopressor: Phenylephrine increases blood pressure by constricting blood vessels.
Indications:
- Nasal congestion due to colds, allergies, or sinusitis
- Sinus pressure and congestion
- Eye redness and itching
- Low blood pressure (hypotension)
Pharmacokinetics:
- Absorption: Rapidly absorbed after oral administration
- Distribution: Widely distributed throughout the body
- Metabolism: Metabolized in the liver
- Excretion: Excreted in the urine
Side Effects:
- Headache
- Dizziness
- Nausea
- Vomiting
- Increased heart rate
- Increased blood pressure
Contraindications:
- Hypersensitivity to Phenylephrine
- High blood pressure (hypertension)
- Heart disease
- Thyroid problems
- Prostate enlargement
Dosage:
- Oral: 10-20 mg, every 4-6 hours
- Injection: 2-5 mg, every 1-2 hours
Forms:
- Tablets
- Capsules
- Liquid
- Injection
- Eye drops
- Nasal spray
Please note that this information is not a substitute for medical advice. If you have any questions or concerns about Phenylephrine or any other medication, please consult a healthcare professional.