Disease Related

PRAZOSIN

Prazosin is an alpha-1 adrenergic blocker used primarily to treat high blood pressure (hypertension) and symptoms of benign prostatic hyperplasia (BPH). It works by relaxing the smooth muscles in blood vessels, leading to vasodilation and reduced blood pressure. In cases of BPH, Prazosin helps to relieve urinary symptoms by relaxing the muscles in the bladder neck and prostate. It is usually administered orally and can cause side effects such as dizziness, orthostatic hypotension, or headaches.

Prazosin is a medication that belongs to the class of alpha-adrenergic blockers. Here is a detailed description:

Chemical Name: 1-(4-Amino-6,7-dimethoxy-2-quinazolinyl)-4-(2-furoyl)piperazine

Molecular Formula: C19H21N5O4

Mechanism of Action:

  • Prazosin works by blocking alpha-1 adrenergic receptors, causing blood vessels to dilate and increasing blood flow.

Indications:

  • Hypertension (high blood pressure)
  • Benign prostatic hyperplasia (BPH)
  • Post-traumatic stress disorder (PTSD)
  • Raynaud’s disease

Pharmacokinetics:

  • Absorption: Well absorbed after oral administration
  • Distribution: Widely distributed throughout the body
  • Metabolism: Metabolized in the liver
  • Excretion: Excreted in the urine

Side Effects:

  • Orthostatic hypotension (low blood pressure when standing)
  • Dizziness
  • Headache
  • Nausea and vomiting
  • Fatigue

Contraindications:

  • Hypersensitivity to Prazosin
  • Coronary artery disease
  • Heart failure
  • Liver disease

Dosage: avoid self medication

  • Oral: 1-20 mg, every 8-12 hours

Forms:

  • Capsules
  • Tablets

Please note that this information is not a substitute for medical advice. If you have any questions or concerns about Prazosin or any other medication, please consult a healthcare professional.