QUIZ- 29 [practice questions]

Effect of fibrates on blood lipids are mediated by

Inhibiting both synthesis & esterification of fatty acids

Their interaction with peroxisome proliferator activated receptors [PPARs]

Reducing the conversion of HMG-CoA to mevalonate

Sequestering bile acids

A cardiovascular selective beta blocker with vasodilating properties is

Pindolo

Atenolol

Bisoprolol

Nebivolol

(-) Hyoscyamine is

15-20 times more active as a mydriatic than (+)-hyoscyamine

Inactive as a mydriatic

3-5 times less active as a mydriatic than (+)-hyoscyamine

100 times more active as a mydriatic (+)-hyoscyamine

In thiazole diuretics, the position 7 is very important and is occupied by a

CH3 group

Free sulphamoyl group

Chloro group

Free- NH2 group

A mass spectrum is obtained by plotting

Molecular weight versus peak height

Concentration versus peak height

Concentration versus degree of deflection of ions

Abundance of ions versus their m/e ratio

Aldehydes can be distinguished from other C=O containing compounds by IR, due to

The low frequency of absorption of aldehydes

The alkyl or group is attached to >C=O

The double bond is present

The doublet at the C-H stretching region

A super disintegrant in tablet formulation is

Sodium Starch glycollate

Starch

PVP

Mg- Aluminum silicate

When ammonium chloride is gradually & slowly incorporates into an emulsion stabilized with ammonium oleate

Emulsion will crack immediately

It will invert from o/w to w/o type

It will invert from w/o to o/w type

There will be no impact on its physical stability

Gram positive bacteria typically contains

Cell wall that lack peptidoglycans

Repeating units arabinogalactan & mycolates in their cellwalls

Peptidoglycan muramic acid & D-amino acids in their cell walls

Cell walls containing pre dominantly polysaccharides & glycoproteins

Quaternary structure of a protein molecule refers to

Specific association to 2 or more copies of a polypeptide chain to result in a biologically active molecule

Regular seen local structure within a polypeptide chain

The portion of the polypeptide chain that comes into contact with another protein molecule

The portion of the structure that gets stabilized upon binding to nucleic acid

QUIZ- 29 [practice questions]

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