TERBUTALINE

Terbutaline is a medication used to manage asthma and other respiratory conditions by relaxing bronchial muscles and dilating airways. It is also used to delay premature labor by relaxing uterine muscles.

The chemical name for Terbutaline is (RS)-5-[2-[(1,1-Dimethylethyl)amino]-1-hydroxyethyl]-1,3-benzodioxole.

The molecular formula is C12H19NO3.

Mechanism of Action:

Terbutaline works by stimulating beta-2 adrenergic receptors, leading to:

  • Relaxation of bronchial muscles
  • Increased heart rate
  • Increased blood sugar levels

Indications include:

  • Asthma
  • Chronic obstructive pulmonary disease (COPD)
  • Premature labor

Pharmacokinetics:

  • Absorption: Rapidly absorbed after oral administration or inhalation
  • Distribution: Widely distributed throughout the body
  • Metabolism: Metabolized in the liver
  • Excretion: Excreted in the urine

Side effects include:

  • Tremors
  • Anxiety
  • Headache
  • Palpitations
  • Nausea and vomiting

Contraindications:

  • Hypersensitivity to Terbutaline
  • Uncontrolled hypertension
  • Severe tachyarrhythmias
  • Heart disease

Dosage: avoid self medication

  • Oral: 2.5-5 mg, every 6-8 hours
  • Inhalation: 1-2 puffs, every 4-6 hours

Forms:

  • Tablets
  • Inhaler
  • Injection

Please note that this information is not a substitute for medical advice. If you have any questions or concerns about Terbutaline or any other medication, please consult a healthcare professional.