SALBUTAMOL

Salbutamol is a medication used to relieve symptoms of asthma and chronic obstructive pulmonary disease (COPD) by relaxing bronchial muscles and opening the airways. It is commonly administered via inhalers for quick relief of wheezing and shortness of breath.

Chemical Name: (RS)-4-[2-[(1,1-Dimethylethyl)amino]-1-hydroxyethyl]-1,3-benzodioxole

Molecular Formula: C13H21NO3

Mechanism of Action:

  • Salbutamol works by stimulating beta-2 adrenergic receptors, leading to:
    • Relaxation of bronchial muscles
    • Increased heart rate
    • Increased blood sugar levels

Indications:

  • Asthma
  • Chronic obstructive pulmonary disease (COPD)
  • Exercise-induced bronchospasm

Pharmacokinetics:

  • Absorption: Rapidly absorbed after inhalation or oral administration
  • Distribution: Widely distributed throughout the body
  • Metabolism: Metabolized in the liver
  • Excretion: Excreted in the urine

Side Effects:

  • Tremors
  • Anxiety
  • Headache
  • Palpitations
  • Nausea and vomiting

Contraindications:

  • Hypersensitivity to Salbutamol
  • Uncontrolled hypertension
  • Severe tachyarrhythmias
  • Heart disease

Dosage: avoid self medication

  • Inhalation: 1-2 puffs, every 4-6 hours
  • Oral: 2-4 mg, every 6-8 hours

Forms:

  • Inhaler
  • Tablets
  • Syrup
  • Injection

Please note that this information is not a substitute for medical advice. If you have any questions or concerns about Salbutamol or any other medication, please consult a healthcare professional.