Tolazoline is a medication that belongs to the class of alpha-adrenergic blockers. Here is a detailed description:
Chemical Name: 2-Benzyl-4,5-dihydro-1H-imidazole
Molecular Formula: C10H12N2
Mechanism of Action:
- Tolazoline works by blocking alpha-adrenergic receptors, causing blood vessels to dilate and increasing blood flow.
Indications:
- Peripheral vascular disease
- Raynaud’s disease
- Erectile dysfunction
- Neonatal hypertension
Pharmacokinetics:
- Absorption: Well absorbed after oral administration
- Distribution: Widely distributed throughout the body
- Metabolism: Metabolized in the liver
- Excretion: Excreted in the urine
Side Effects:
- Headache
- Dizziness
- Nausea and vomiting
- Flushing
- Hypotension
Contraindications:
- Hypersensitivity to Tolazoline
- Severe coronary artery disease
- Heart failure
- Glaucoma
Dosage: avoid self medication
- Oral: 25-50 mg, every 6-8 hours
- Intravenous: 1-2 mg/kg, every 6-8 hours
Forms:
- Tablets
- Injection
Please note that this information is not a substitute for medical advice. If you have any questions or concerns about Tolazoline or any other medication, please consult a healthcare professional.